[institut] Najava seminara

[Aleksandar Milosavljevic]

Поштоване колегинице и колеге,

 

Позивам вас на С Е М И Н А Р:

 

"Investigation of biomolecular processes using DNA origami nanostructures"

 

који ће у уторак 24. марта 2015. године са почетком у 11 часова у сали “Звонко Марић” Института за физику у Београду одржати Проф. Илко Балд са Универзитета у Потсдаму. Сажетак предавања је дат у наставку поруке.

 

Срдачан поздрав,

 

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Др Александар Милосављевић

Виши научни сарадник

Институт за физику у Београду

Прегревица 118

11080 Београд

 

телефон: +381 11 3713 007

http://mail.ipb.ac.rs/~vraz/

 

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"Investigation of biomolecular processes using DNA origami nanostructures"

 

DNA origami nanostructures allow for the arrangement of different functionalities such as specific DNA structures, nanoparticles, proteins and various chemical modifications with unprecedented precision [1]. The arranged functional entities can be visualized by atomic force microscopy (AFM), and spectroscopically characterized for instance using surface enhanced Raman scattering (SERS) and fluorescence spectroscopy. In the presentation three topics will be discussed, in which functionalized DNA nanostructures are used: (i) The investigation of fundamental mechanisms of DNA radiation damage at a single-molecular level, more precisely, the nucleotide sequence dependence of radiation induced DNA strand breaks [2]. (ii) The fabrication of plasmonic nanostructures, which can be used for highly-sensitive SERS measurements down to the single-molecule level [3]. (iii) The selective formation of guanine quadruplex structures on DNA origami substrates, which is studied by Förster resonant energy transfer (FRET) [4].

 

[1]    I. Bald and A. Keller, Molecules 19, 9 (2014).

[2]    a) A. Keller et al., Sci. Rep., 4 (2014); b) A. Keller, J. Kopyra, K. V. Gothelf, and I. Bald, New J. Phys. 15 (2013); c) A. Keller et al., ACS Nano 6, 5 (2012); 

[3]    J. Prinz et al., J. Phys. Chem. Lett. 4, 23 (2013).

[4]          L. Olejko, P. J. Cywinski, and I. Bald, Angew. Chem. Int. Ed. 54 (2015).

 

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JProf. Dr. Ilko Bald

Universität Potsdam
Institut für Chemie - Physikalische Chemie
Karl-Liebknecht-Straße 24-25, Haus 29, Raum 0.08
D-14476 Potsdam-Golm

BAM Bundesanstalt für Materialforschung und -prüfung

Abteilung 1 - Analytische Chemie und Referenzmaterialien

Richard-Willstätter Str. 11

D-12489 Berlin

 

e-mail: bald at uni-potsdam.de

www.uni-potsdam.de/osci

 

 

 

 

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