[institut] Lecture Announcement: PBPK Modeling – Dr. Jasmina Novaković, August 26
Darija Obradović
darija at ipb.ac.rs
Tue Aug 18 14:21:20 CEST 2026
Dear colleagues,
I am pleased to invite you to a lecture by Dr. Jasmina Novaković
entitled:
PBPK Modeling: Principles and Applications in Drug Development
Wednesday, August 26, 2026
12:00–13:00
Dr. Dragan Popović Lecture Hall, Institute of Physics Belgrade
Speaker Biography
Dr. Jasmina Novaković is a pharmaceutical scientist currently working in
Canada as a Senior PBPK Consultant at Certara, Simcyp Division. She has
more than two decades of international experience in drug development,
research, education, and scientific consulting, with a particular focus
on computational modeling and simulation within the framework of
Model-Informed Drug Development (MIDD) and physiologically based
pharmacokinetic (PBPK) modeling.
Prior to joining Certara, she was Principal Scientist for PBPK Modeling
at Simulations Plus (2019–2025) and held a scientific leadership
position in research and development at Apotex in Toronto (2007–2019).
She also conducted research in preclinical drug development at the
University of Toronto and taught clinical pharmacology at Seneca
Polytechnic in Toronto. Earlier in her career, she worked in
pharmaceutical research in Prague and at the Faculty of Pharmacy,
University of Belgrade.
Dr. Novaković is active in the international pharmaceutical science
community and has been an invited speaker at numerous scientific
conferences, workshops, and professional meetings. She has served on the
United States Pharmacopeia (USP) Expert Group for Small Molecules since
2015 and has been a member of the Board of Directors of the Canadian
Society for Pharmaceutical Scientists (CSPS) since 2025.
Lecture Abstract
In this lecture, Dr. Novaković will introduce the fundamental principles
of physiologically based pharmacokinetic (PBPK) modeling and discuss its
applications in modern drug development.
PBPK models integrate information about the physicochemical and
pharmacokinetic properties of biologically active molecules with
mathematical descriptions of human physiology to simulate and predict
drug absorption, distribution, metabolism, and elimination.
This approach is closely related to the emerging concept of digital
twins in biomedicine. By creating computational representations of
biological systems, simulations can be used to explore and predict how
biologically active molecules behave in the human body under different
physiological conditions, including variability between individuals and
populations. Such in silico approaches can complement experimental and
clinical studies and increasingly contribute to decision-making
throughout the drug-development process.
The lecture will provide an opportunity to learn about a rapidly
developing field at the intersection of physics, computational modeling,
mathematics, biology, pharmacology, and medicine, and to discuss how
computational simulations and digital-twin approaches can contribute to
predicting the behavior of biologically active molecules.
I hope you will be able to join us.
Best regards,
Dr. Darija Obradović
Biomimetics Laboratory
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